Christian Weyer provides a nice overview of WS-* support in the current and upcoming Web Service technology stacks in the .NET world. He only includes out-of-the-box functionality, but many folks are providing additional transports, WS-* specs, etc. for WSE and WCF. As they say, your mileage may vary, but this is a great starting point when trying to figure out the WS-* smörgåsbord. (Yes, I had to look up that up on Meriam-Webster to be sure of the spelling.) :-)